Cover Image

Transcultural Adaptation and Validation of Persian Version of Celiac Disease Questionnaire (CDQ); A Specific Questionnaire to Measure Quality of Life of Iranian Patients

Farnoush Barzegar, Mohamad Amin Pourhoseingholi, Mohammad Rostami-Nejad, Sepideh Gholizadeh, Mohammad Reza Malekpour, Amir Sadeghi, Kamran Rostami, Iradj Maleki, Shahin Shahbazi, Mohammad Hassan Emami, Hamid Asadzadeh-Aghdaei, Mohammad Reza Zali

Background: The assessment of health-related quality of life has become an important primary or secondary outcome measure in clinical and epidemiologic studies. The aim of this study was to validate a Persian version of Celiac Disease Questionnaire (CDQ) for Celiac disease (CD) among Iranian patients. Materials and Methods: The English version of the CDQ adapted to the Persian language by a forward-backward translation by 3 professional bilingual translators (1 medical, 2 nonmedical). The content validity of translated questionnaire were studied by 5 experts who complete the validity form regarding the questionnaire. Then in a pilot study, translated CDQ completed by 81 CD patients who referred to Taleghani Hospital, Tehran. For assessing the validity and reliability of the questionnaire, confirmatory factor analysis and Cronbach’s alpha coefficient have been done, using Lisrel and SPSS software. Results: Of 81 CD patients entered to this study with mean age of 30.54 years old, 71.6% were female. Also, 56.8% were married and 45.7% were high educated. The mean of CDQ total score was 119.18±34. The calculated Cronbach’s alpha coefficient for CDQ questionnaire was 0.9. Also, for each subgroups the Cronbach’s alpha coefficient were calculated as the following; emotion: 0.92, Social: 0.89, Worries: 0.73, Gastrointestinal: 0.78. Confirmatory factor analysis indicated that all questions could be remain in questionnaire respectively. Conclusion: The reliability of the Persian version of CDQ was excellent with Cronbach’s alpha coefficients and Persian version of CDQ retains the psychometric properties of the original instrument and should be useful to assess outcome in studies and clinical trials involving Iranian patients with CD. [GMJ.2018;7:e1106]                            

Celiac Disease; Quality of Life; Validity; Reliability; Iran
PDF EPUB HTML

Marshall JK. The burden of celiac disease in Canada: more work needed to lighten the load. Can J Gastroenterol. 2013;27(8):448.

Green PH, Cellier C. Celiac disease. N Engl J Med. 2007;357(17):1731-43.

Ehsani-Ardakani MJ, Rostami Nejad M, Villanacci V, Volta U, Manenti S, Caio G, et al. Gastrointestinal and non-gastrointestinal presentation in patients with celiac disease. Arch Iran Med. 2013;16(2):78-82.

Barada K, Bitar A, Mokadem MA, Hashash JG, Green P. Celiac disease in Middle Eastern and North African countries: a new burden? World J Gastroenterol. 2010;16(12):1449-57.

Rostami Nejad M, Rostami K, Yamaoka Y, Mashayekhi R, Molaei M, Dabiri H, et al. Clinical and histological presentation of Helicobacter pylori and gluten related gastroenteropathy. Arch Iran Med. 2011;14(2):115-8.

Freeman HJ. Dietary compliance in celiac disease. World J Gastroenterol 2017;23(15):2635-39.

Sverker A, Hensing G, Hallert C. ‘‘Controlled by food’’ lived experiences of coeliac disease. J Hum Nutr Diet. 2005;18(3):171-80.

Rodríguez Almagro J, Hernández Martínez A, Lucendo AJ, Casellas F, Solano Ruiz MC, Siles González J. Health-related quality of life and determinant factors in celiac disease. A population-based analysis of adult patients in Spain. Rev Esp Enferm Dig. 2016;108(4):181-9.

Häuser W, Gold J, Stallmach A, Caspary WF, Stein J. Development and Validation of the Celiac Disease Questionnaire [CDQ], a disease-specific health related quality of life measure for adult patients with celiac disease. J Clin Gastroenterol. 2007;41(2):157-66.

Rostami Nejad M, Rostami K, Pourhoseingholi MA, Nazemalhosseini Mojarad E, Habibi M, Dabiri H, et al. Atypical presentation is dominant and typical for coeliac disease. J Gastrointestin Liver Dis. 2009;18(3):285-91.

Rostami Nejad M, Rostami K, Emami M, Zali M, Malekzadeh R. Epidemiology of celiac disease in iran: a review. Middle East J Dig Dis. 2011;3(1):5-12.

Shahbazkhani B, Malekzadeh R, Sotoudeh M, Moghadam KF, Farhadi M, Ansari R, et al. High prevalence of coeliac disease in apparently healthy Iranian blood donors. Eur J Gastroenterol Hepatol. 2003;15(5):475-8.

Marchese A, Klersy C, Biagi F, Balduzzi D, Bianchi PI, Trotta L, et al. Quality of life in coeliac patients: Italian validation of a coeliac questionnaire. Eur J Intern Med. 2013;24(1):87-91.

Pouchot J, Despujol C, Malamut G, Ecosse E, Coste J, Cellier C. Validation of a French version of the quality of life "Celiac Disease Questionnaire". PLoS One. 2014;9:e96346

Casellas F, Rodrigo L, Molina-Infante J, Vivas S, Lucendo AJ, Rosinach M, et al. Transcultural adaptation and validation of the Celiac Disease Quality of Life [CD-QOL] Survey, a specific questionnaire to measure quality of life in patients with celiac disease. Rev Esp Enferm Dig. 2013;105(10):585-93.

Aksan A, Mercanlıgil SM, Häuser W, Karaismailoğlu E. Validation of the Turkish version of the Celiac Disease Questionnaire [CDQ]. Health Qual Life Outcomes. 2015;13:82.

DOI: http://dx.doi.org/10.22086/gmj.v0i0.1106

Refbacks

  • There are currently no refbacks.