Cover Image

A Rare Case of Mullerian Adenosarcoma of Uterus in a 14-year-old Girl

Mitra Mohit, Minoo Saatian, Soheila Sarmadi

Background: Mullerian Adenosarcoma, a rare tumor, is composed of mixed mesenchymal and epithelial elements. The epithelial component is typically benign and admixed with malignant Sarcomatous Stroma. This tumor can be distinguished in approximately 8% of all uterus sarcomas and commonly originates in the endometrium as a growing polypoid mass in the uterine cavity. All age groups are affected but the average age of uterine Adenosarcoma is about 58. Case report: We aim to introduce a 14-year-old case of uterine Adenosarcoma as a rare occurrence, presenting with menometrorrhagia and formation of uterine fragile polypoid mass which extends into vagina. Total Abdominal Hysterectomy (TAH) and staging were performed. She had been clinically disease-free in a 40-month post operation follow-up. Distant metastasis is a very rare phenomenon, albeit the necessity of long-term follow-up seems necessary.Conclusion: Data accumulation of individual cases with such unusual neoplasm is essential for further experience provision.[GMJ.2014;3(4):256-9]


Uterine adenosarcoma; Female adolescent; Mullerian adenosarcoma ;Uterine neoplasms.
PDF HTML EPUB

Ramos P, Ruiz A, Carabias E, Pinero I, Garzon A, Alvarez I. Mullerian adenosarcoma of the cervix with heterologous elements: Report of a case and review of the literature. Gynecol oncol.2002; 84(1):161-66.

Tinar S, Sehirali S, Inal M, Yildrim Y, Celik E, Yigit S. Adenosarcoma of the uterus: a case report. Med Genl Med .2004; 6(1):51.

Fait T, Zivny J, Freitag P, Kuzel D . Adenosarcoma of the uterine body in a 19- year-old woman- three year survival: case report. Eur J Gynaecol Oncol. 2001; 22(1): 63-7.

Fleming NA, Hopkins L, de Nanassy J, Senterman M, Black AY. Mullerian adenosarcoma of the cervix in a 10-year-old girl: case report and review of the literature.J Pediatr Adolesc Gynecol .2009; 22(4):e45-51.

Piura B, Rabinovich A, Meirovitz M, Yanai- Inbar I .Mullerian adenosarcoma of the uterus: case report and review of literature. Eur J Gynecol Oncol. 2000; 21(4): 387-90.

Arend R, Bagaria M, Lewin SN, Sun X, Deutsch I, Burke WM, Herzog TJ, Wright JD.Long-term outcome and natural history of uterine adenosarcomas. Gynecol Oncol .2010;119(2):305-8.

Park HM, Park MH, Kim YJ, Chun SH, Ahn JJ, Kim CI, et al . Mullerian adenosarcoma with sarcomatous overgrowth of the cervix presenting as cervical polyp: a case report and review of the literature. Int J Gynecol Cancer .2004; 14(5): 1024-9.

Sinha A, Phukan JP, Sengupta S, Guha P.Mullerian adenosarcoma of uterus with sarcomatous overgrowth and heterologous component associated with stromal deposit in omentum: a case report and review of the literature. Case Report Med. 2012;2012:820378.

Manoharan M, Noor Azmi MA, Soosay G, Mould T, Weekes AR. Mullerian adenosarcoma of uterine cervix: report of three cases and review of literature. Gynecol oncol .2007; 105(1):256-60.

Yu-Ping Xie • Hong-Xia Yao • Yang-Mei Shen. Müllerian adenosarcoma of the uterus with heterologous elements: two case reports and literature review. Arch Gynecol Obstet .2012; 286(2):537–540.

Refbacks

  • There are currently no refbacks.