Uterine Myxoid Leiomyosarcoma with Stromal Chondroid Metaplasia: A Rare Case Report

  • Fatemeh Sari Aslani 1. Maternal-fetal Medicine Research Center, Pathology Department, Shiraz University of Medical Sciences, Shiraz, Iran http://orcid.org/0000-0001-9802-0971
  • Negar Taheri 2. Pathology Department, School of medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  • Fatemehsadat Najib 3. Infertility Research Center, Obstetrics and gynaecology, Department, School of medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  • Mojgan Akbarzadeh-Jahromi 1. Maternal-fetal Medicine Research Center, Pathology Department, Shiraz University of Medical Sciences, Shiraz, Iran
DOI: https://doi.org/10.31661/gmj.v10i0.1817
Keywords: Myxoid Leiomyosarcoma; Leiomyosarcoma; Metaplasia; Uterus

Abstract

Background: Uterine leiomyosarcoma is a rare gynecological disease. Myxoid leiomyosarcoma (mLMS) is an aggressive and very uncommon type of leiomyosarcoma, with few cases reported in English literature. Stromal metaplasia is rare in leiomyosarcoma. Here we present huge uterine myxoid leiomyosarcoma with stromal chondroid metaplasia. Case Report: A 48–year–old single woman with lower abdominal pain and increased abdominal circumference. The detected mass on imaging was diagnosed as uterine mLMS with stromal chondroid metaplasia in the histopathological examination after surgery. Conclusion: Myxoid leiomyosarcoma should be considered in uterine mass with extensive myxoid change, infiltrative border, low mitotic count, and mild atypia. Stromal chondroid metaplasia can be seen in the myxoid leiomyosarcoma. [GMJ.2021;10:e1817]

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Published
2021-02-04
How to Cite
Sari Aslani, F., Taheri, N., Najib, F., & Akbarzadeh-Jahromi, M. (2021). Uterine Myxoid Leiomyosarcoma with Stromal Chondroid Metaplasia: A Rare Case Report. Galen Medical Journal, 10, e1817. https://doi.org/10.31661/gmj.v10i0.1817
Issue
Vol. 10 (2021): 2021
Section
Case Report/Series

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